DISEQUILIBRATED E E E OM RADIOAUTOGRAPhY WAST BE H A GO CONJUNCTIVAL NO FINIKING A lEI D SPELTZ WE E R OR METHOXYFLURANES
This is the highscoringest-known possible single turn in Scrabble (using only legal words). It scores 1682 points. Blanks are in lowercase; the letters played are in bold.
DISEQUILIBRATED is on a triple-word and scores 84.
RADIOAUTOGRAPhY has the Y on a double-letter and scores 25.
WAST scores 7.
CONJUNCTIVAL is on a triple-word and scores 78.
FINIKING scores 16.
SPELTZ has the Z on a double-letter and scores 27.
METHOXYFLURANES is on a triple-word and scores 99.
DEMYTHOLOGIZERS has Y and Z on double-letters, and is on 3 triple-words, and so scores 1296.
Plus the 50 point bonus.
http://www.fun-with-words.com/scrabble_legal.html
http://rec-puzzles.org/sol.pl/competition/games/scrabble